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發布日期: 2010年1月1日
一項Cochrane系統性回顧評估了預防癌症患者口腔黏膜炎的介入措施，發現冷凍療法（冰塊）在預防黏膜炎方面顯示出益處。此評估評估了多項隨機對照試驗，這些試驗納入了接受包括骨髓移植在內的各種癌症治療的不同類型癌症患者。在所有評估的黏膜炎預防策略中，冷凍療法是僅有的兩種介入措施之一（另一種是角質細胞生長因子），其療效證據最為充分。
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