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Yayınlandı: 1 Ocak 2010
Kanser hastalarında oral mukoziti önlemeye yönelik müdahaleleri değerlendiren bir Cochrane sistematik incelemesi, kriyoterapinin (buz parçaları) mukoziti önlemede fayda sağladığını ortaya koymuştur. İnceleme, kemik iliği nakli de dahil olmak üzere çeşitli kanser tedavileri gören farklı kanser türlerine sahip hastalarda yapılan çok sayıda randomize kontrollü çalışmayı değerlendirmiştir. Kriyoterapi, mukozit önleme için değerlendirilen tüm stratejiler arasında en güçlü fayda kanıtını gösteren yalnızca iki müdahaleden biriydi (keratinosit büyüme faktörü ile birlikte).
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