Authors: Cummings, John, Mann, Jim, Mete, Evelyn, Reynolds, Andrew, Te Morenga, Lisa, Winter, Nicola
Published: February 2, 2019
Analysis of 185 prospective studies with nearly 135 million person-years demonstrated a 15-30% decrease in type 2 diabetes incidence comparing highest versus lowest dietary fibre consumers. Dose-response curves identified 25-29g/day as the threshold for greatest risk reduction, with evidence suggesting higher intakes could confer even greater protection. Striking dose-response evidence supported a potentially causal relationship. Evidence certainty was graded as moderate under the GRADE framework. Robustness was confirmed through sensitivity analyses, meta-regression, dose-response testing, and subgroup analyses using random-effects models.
