Smoking cessation

Suggested

2 studies · 1 recommendation

Last updated: February 25, 2026

Suggested2 studies

Structured smoking cessation programs effectively treat nicotine dependence with strong cost-effectiveness

A comprehensive PHS clinical practice guideline synthesizing over 8,700 research articles (1975–2008), reviewed by 37 experts from 8 federal and nonprofit organizations including AHRQ, CDC, NCI, and NIDA, identified clinically validated tobacco dependence treatments across diverse populations. A health economic evaluation of 1,131 smokers enrolled in the Swedish national quitline found a 31% abstinence rate at 12 months, with 2,400 accumulated life years saved. Cost per quitter ranged from $1,052 to $1,360, while cost per life year saved was $311 to $401—remaining cost-effective even at a reduced 20% abstinence rate ($482 per life year saved). Discounted rates confirmed strong value at $135–$283 per life year saved. These two studies demonstrate that formal cessation interventions deliver measurable quit rates and exceptional cost-effectiveness for nicotine dependence treatment.

Evidence

Quitline in smoking cessation : a cost-effectiveness analysis

Authors: Gilljam, Hans, Helgason, Ásgeir R., Tomson, Tanja

Published: August 24, 2012

A health economic evaluation of the Swedish national quitline assessed 1,131 callers enrolled between February 2000 and November 2001. Of these smokers, 354 (31%) reported abstinence after 12 months of follow-up. The accumulated life years saved in the study population totaled 2,400. Cost per quitter ranged from 1,052 to 1,360 USD, while cost per life year saved was 311 to 401 USD. Sensitivity analysis demonstrated that even at a reduced abstinence rate of 20%, the cost per life year saved rose only modestly to 482 USD. Discounted cost per life year saved was 135 USD at 3% and 283 USD at 5%, confirming the intervention as cost-effective compared with alternative smoking cessation programs.

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Smoking cessation

Authors: United States Tobacco Use and Dependence Guideline Panel.

This PHS-sponsored clinical practice guideline synthesized over 8,700 research articles published between 1975 and 2008, reviewed by a panel of 37 experts from 8 federal and nonprofit organizations including AHRQ, CDC, NCI, NHLBI, and NIDA. The guideline identifies clinically effective tobacco dependence treatments validated through experimental evidence. The update builds on approximately 3,000 articles from the 1996 guideline, 3,000 additional articles for the 2000 update, and 2,700 new articles for this 2008 edition, establishing a comprehensive evidence base for tobacco cessation interventions across diverse populations.

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