Authors: Fu, Wenning, Gan, Yong, Jiang, Heng, Li, Hui, Lu, Zuxun, Lyu, Chuanzhu, Song, Fujian, Wang, Chao, Xu, Hongbin, Yan, Shijiao, Yang, Wei
Published: September 14, 2019
Meta-analysis of 18 observational studies (17 case-control, 1 prospective cohort) involving 202,969 individuals and 5,517 lung cancer patients. Comparing highest versus lowest carrot consumption, the pooled OR was 0.58 (95% CI 0.45–0.74), indicating a 42% lower risk. Subgroup analysis by lung cancer type showed the strongest association for adenocarcinoma (OR 0.34, 95% CI 0.15–0.79) and mixed types (OR 0.61, 95% CI 0.46–0.81). Results for squamous cell carcinoma (OR 0.52, 95% CI 0.19–1.45), small-cell carcinoma (OR 0.43, 95% CI 0.12–1.59), and large-cell carcinoma (OR 0.40, 95% CI 0.10–1.57) showed non-significant reductions. Sensitivity analysis confirmed stability of findings.
