Illness Researcher

Dietary Cholesterol

Caution

1 studies · 1 recommendation

Last updated: February 15, 2026

Caution1 studies

Higher dietary cholesterol intake associated with increased laryngeal cancer risk

Dietary cholesterol intake showed one of the strongest associations with laryngeal cancer risk in this study. Reducing intake of cholesterol-rich foods such as organ meats, egg yolks, and fatty animal products may help lower risk.

Evidence

Energy, macronutrients and laryngeal cancer risk

Authors: Bosetti, Cristina, Franceschi, Silvia, Fryzek, J., Garavello, Werner, La Vecchia, Carlo, Levi, Fabio, McLaughlin, J.K., Negri, Eva, Talamini, Renato

Published: January 1, 2003

In a case-control study of 527 laryngeal cancer cases and 1297 controls from Italy and Switzerland, higher cholesterol intake was associated with a significantly elevated risk of laryngeal cancer, with a continuous OR of 1.43 (95% CI 1.19-1.71). Cases consistently reported higher dietary cholesterol consumption than controls. Analysis used unconditional multiple logistic regression adjusting for relevant confounders including alcohol and tobacco use. The association was among the strongest observed across all macronutrients examined.

COREView Source →