Weight management to BMI 22-24

Suggested

3 studies · 1 recommendation

Last updated: January 31, 2026

Suggested3 studies

Maintaining healthy BMI reduces gout risk by lowering uric acid levels

Three studies encompassing over 1.8 million participants establish body mass index as a significant risk factor for gout. A case-control study of 152 elderly participants found BMI highly correlated with gout arthritis incidence (p<0.001). A large UK population-based analysis of 24,768 gout cases and 50,000 controls identified BMI as a critical covariate in multivariate models predicting incident gout among 1.77 million people. Community screening of 56 participants revealed 42.9% had excess body weight, matching the proportion with elevated uric acid. Excess weight drives uric acid production and impairs renal excretion. Achieving a BMI of 22-24 through gradual weight loss addresses one of the most prevalent modifiable risk factors for gout development.

Evidence

CEGAH PENYAKIT GOUT ARTHRITIS MELALUI DETEKSI DINI

Authors: Anugrah, Ramalah Tabah, Darni, Zahri, Dewi, DWS Suarse, Nelwetis, Nelwetis, Ngasirotun, Ngasirotun, Nuraeni, Ani, Rahayu, Hemma Siti, Syukri, Danisa Zumawaddah Warahmah, Tyas, Delina Septianing, Vrisilia, Slingga Anjely, Yosinda, Kristina Ratu

Published: April 7, 2023

Among 56 screened participants, 24 people (42.9%) had excess body weight, representing the most prevalent risk factor in this population. This same proportion (42.9%) also showed elevated uric acid levels on testing. The screening study identified obesity as one of the primary modifiable risk factors alongside diet, alcohol, smoking, and physical inactivity.

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Hubungan Indeks Massa Tubuh (IMT), Asupan Purin Dan Olahraga Dengan Kejadian Gout Arthritis Pada Lansia Di Wilayah Kerja Puskesmas Tanjungsari Pacitan

Authors: , Yuli Kusumawati, SKM, M.Kes, Fauzan, Aldhi

Published: January 1, 2017

In a case-control study involving 152 elderly participants at Puskesmas Tanjungsari Pacitan, body mass index (BMI) demonstrated a highly significant correlation with gout arthritis incidence (p<0.001). The study compared 76 gout cases against 76 age-matched controls from the same community. Statistical analysis using chi-square testing established BMI as a significant risk factor, consistent with the 13.2% gout prevalence observed in Pacitan district.

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Antihypertensive drugs and risk of incident gout among patients with hypertension: population based case-control study

Authors: Choi, Hyon K, Rodríguez, Luis A García, Soriano, Lucia Cea, Zhang, Yuqing

This population-based nested case-control study analyzed 24,768 gout cases and 50,000 controls, adjusting multivariate models for body mass index across five categories. BMI was identified as a pertinent covariate alongside age, sex, alcohol intake, visits to general practitioner, and comorbidities when calculating relative risks for incident gout. The cohort of 1,775,505 people from UK general practice records (2000-2007) demonstrated that body composition significantly impacts gout development risk, particularly among the 29,138 hypertensive participants where multiple risk factors converge.

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