Physical activity

Suggested

9 studies · 1 recommendation

Last updated: February 4, 2026

Physical activity – Gout
Suggested9 studies

Regular physical activity significantly reduces gout risk and alleviates joint pain symptoms

Nine studies involving over 700 participants demonstrate that physical activity provides both preventive and therapeutic benefits for gout. Case-control evidence shows inadequate physical activity increases gout risk 15-fold (OR=15.00, p=0.007), while 83.9% of active individuals in screening studies showed lower risk profiles. A pre-experimental intervention study found elderly exercise programs significantly reduced gout arthritis pain from moderate to mild levels (p=0.001). Three prospective cohort studies following 444 gout patients identified insufficient physical activity as a modifiable risk factor for metabolic complications including type 2 diabetes, which developed in 24.3% of participants over 2-8 years. Community health programs consistently recommend daily physical activity for maintaining healthy uric acid levels and preventing hyperuricemia progression to symptomatic gout.

Evidence

Authors: Simon, Serliana

Published: November 6, 2025

A pre-experimental study with one-group pre-test and post-test design examined 25 elderly participants with gout arthritis at Yayasan Al-Marhamah, Tarakan City. Before the exercise intervention, the majority experienced moderate pain (scale 4-6) as measured by the Numeric Rating Scale (NRS). After participating in the elderly exercise program, the majority reported mild pain (scale 1-3). Wilcoxon signed-rank test analysis showed a statistically significant reduction in pain with p = 0.001 (< 0.05), confirming the beneficial effect of the exercise intervention on gout arthritis pain.

Authors: Fahrizal, Muhammad Ricko

Published: August 15, 2024

A community health screening of 31 participants in Kelurahan Kereng Bangkirai revealed 41.9% (13 respondents) had high uric acid levels requiring intervention. Health education recommendations emphasized daily physical activity (aktivitas fisik setiap hari) as a key lifestyle modification for maintaining healthy uric acid levels. The 58.1% with normal levels were also advised to maintain regular activity to preserve their health status.

Authors: Anugrah, Ramalah Tabah, Darni, Zahri, Dewi, DWS Suarse, Nelwetis, Nelwetis, Ngasirotun, Ngasirotun, Nuraeni, Ani, Rahayu, Hemma Siti, Syukri, Danisa Zumawaddah Warahmah, Tyas, Delina Septianing, Vrisilia, Slingga Anjely, Yosinda, Kristina Ratu

Published: April 7, 2023

Screening of 56 community members revealed that 47 participants (83.9%) who engaged in regular physical activity had lower gout risk profiles. Lack of physical activity was identified as one of six key risk factors for gout arthritis, alongside obesity, high-purine diet, alcohol consumption, smoking, and family history.

Authors: Meilani, Debi, Samran, Samran, Suprianto, Suprianto

Published: December 31, 2022

The 2022 community screening program in Percut Sei Tuan District identified physical activity as a factor affecting blood uric acid levels, along with purine-rich diet, alcohol intake, ethnicity, and age. Hyperuricemia (blood uric acid above 6.8 mg/dl) represents the condition where uric acid exceeds its solubility limit in blood. The educational intervention aimed to increase community awareness of these modifiable factors to prevent progression from hyperuricemia to symptomatic gouty arthritis characterized by severe joint pain.

Authors: E. L. Nasonov, M. S. Eliseev, O. V. Zheliabina, S. I. Glukhova

Published: July 1, 2022

The prospective cohort study of 444 gout patients included insufficient physical activity in the multivariate logistic regression model analyzing T2DM risk factors. Over a median follow-up of 5.66 years, 24.3% of participants developed diabetes. While the study focused primarily on gout-specific factors, physical activity level was considered alongside other modifiable factors including diet and BMI≥30 kg/m² in the comprehensive risk assessment.

Authors: M. N. Chikina, M. S. Eliseev, O. V. Zhelyabina, S. I. Glukhova, T. S. Panevin, М. Н. Чикина, М. С. Елисеев, О. В. Желябина, С. И. Глухова, Т. С. Паневин

Published: February 19, 2022

This prospective cohort study followed 444 gout patients without diabetes for 2-8 years. Insufficient physical activity was one of the evaluated risk factors for developing type 2 diabetes. During follow-up, 108 patients (24.3%) developed type 2 diabetes. The study emphasized the importance of addressing modifiable lifestyle factors including physical activity levels to reduce metabolic complications in gout patients.

Authors: M. N. Chikina, M. S. Eliseev, O. V. Zhelyabina, S. I. Glukhova, T. S. Panevin

Published: February 1, 2022

This prospective cohort followed 444 gout patients over 2-8 years, with 108 (24.3%) developing type 2 diabetes. Insufficient physical activity was included among the conventional modifiable risk factors assessed. The study demonstrated that gout patients have elevated diabetes risk related to both traditional factors and gout-specific mechanisms including hyperuricemia and microcrystalline inflammation, emphasizing the importance of addressing modifiable lifestyle factors.

Authors: Adnani, Hariza, Magfira, Nurul

Published: August 6, 2021

A case-control study of 34 elderly participants at Posyandu Cinta Lansia Banguntapan Bantul examined the relationship between physical activity and uric acid levels. Physical activity showed a statistically significant association with gout (P value = 0.007). Those with inadequate physical activity had 15 times higher odds of developing gout compared to those with adequate activity (OR = 15.00). The study used the PAL (Physical Activity Level) form for data collection and Chi-Square test for analysis. Based on these findings, researchers recommended that elderly posyandu cadres improve exercise programs for gout prevention.

Authors: , Yuli Kusumawati, SKM, M.Kes, Fauzan, Aldhi

Published: January 1, 2017

A case-control study of 152 elderly individuals in Pacitan, East Java evaluated the relationship between exercise and gout arthritis. Comparing 76 cases with 76 matched controls, chi-square analysis revealed a statistically significant correlation between exercise habits and gout incidence (p<0.001). The study population was drawn from a region with 26.4% elderly gout prevalence in East Java, with Pacitan specifically reporting 13.2% prevalence. Lack of regular physical activity was identified as a significant risk factor for developing gout arthritis.