Cinnamon

Suggested

3 studies · 1 recommendation

Last updated: January 31, 2026

Suggested3 studies

Cinnamon decoction with honey may lower uric acid levels in gout patients

Three non-randomized interventional studies with a combined 74 gout patients examined cinnamon's effects on uric acid and pain. In two Indonesian quasi-experimental studies totaling 50 patients, 15% cinnamon decoction with honey administered once daily for one week produced significantly lower uric acid levels compared to Allopurinol 100 mg (p=0.023). A third study with 24 patients found cinnamon decoction significantly reduced pain scores (p=0.000), performing comparably to bay leaf decoction. The proposed mechanism involves cinnamaldehyde (68.65% concentration in extracts), a polyphenol that inhibits xanthine oxidase enzyme activity involved in uric acid production. While these preliminary findings suggest potential benefit, the evidence comes exclusively from small quasi-experimental studies without randomization or blinding.

Evidence

Comparison Stew Bay Leaf ( Syzygium Polyanthus ) With Stew Cinnamon ( Cinnamomun Burmese ) To Decrease Scale Painful On Sufferer Arthritis Gout In The Workplace Health Center Baiturrahman City of Banda Aceh

Authors: Desreza, Nanda, Iskandar, Iskandar, Maiyumna, Maiyumna

Published: October 26, 2025

A quasi-experimental study using pre-test post-test and between two group design included 24 gout arthritis patients. Twelve respondents received cinnamon decoction, demonstrating statistically significant reduction in pain scale with p-value = 0.000. The study compared cinnamon decoction with bay leaf decoction and found no significant difference between the two interventions (p = 0.196), indicating both herbal decoctions achieved comparable pain reduction outcomes in this non-randomized interventional trial.

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Therapy of Cinnamon Decoction using Honey in Reducing Gout

Authors: Nurhayati, Yeti, Umarianti, Tresia

Published: January 1, 2019

A quasi-experimental study with pre and post-test design conducted at Gambirsari Community Health Center, Surakarta, Indonesia enrolled 50 gout patients divided into two groups of 25 each. The treatment group received 15% concentration cinnamon decoction with honey once daily for one week, while the control group received Allopurinol 100 mg once daily for the same duration. Statistical analysis using Wilcoxon and Mann-Whitney tests showed that uric acid levels in the cinnamon-honey decoction group were significantly lower than in the control group (p=0.023). The cinnamon extract's high cinnamaldehyde content (68.65%) provides antioxidant properties that inhibit xanthine oxidase enzyme activity.

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Therapy of Cinnamon Decoction Using Honey in Reducing Gout

Authors: Nurhayati, Y. (Yeti), Umarianti, T. (Tresia)

Published: January 1, 2018

A quasi-experimental pre-post study conducted in Surakarta, Central Java enrolled 50 gout patients divided into two groups of 25 each using quota sampling. The treatment group received 15% concentration cinnamon decoction with honey once daily for one week, while the control group received Allopurinol 100 mg once daily for the same duration. Statistical analysis using Wilcoxon and Mann-Whitney tests showed uric acid levels in the cinnamon-honey decoction group were significantly lower than the control group (p=0.023). The cinnamon extract contains cinnamaldehyde at 68.65% concentration, a polyphenol with antioxidant properties that may inhibit xanthine oxidase enzyme involved in uric acid metabolism.

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