Illness Researcher

Vegetables

Suggested

2 studies · 1 recommendation

Last updated: February 25, 2026

Vegetables – Gastric Cancer
Suggested2 studies

Higher vegetable intake linked to lower gastric cancer risk in case-control analyses

Two case-control studies totaling 440 participants (146 gastric cancer patients and 294 healthy controls) examined the association between vegetable consumption and gastric cancer risk. In an Iranian study of 128 adults, low fresh vegetable intake ranked among the most significant dietary risk factors for gastric cancer (P<0.05). A second study comparing 104 non-cardia gastric cancer patients with 208 controls found significantly lower vegetable consumption in the cancer group (p=0.02), though this association did not maintain independent significance after multivariate adjustment for genetic and lifestyle factors. Both studies support a protective role for regular vegetable intake as part of a dietary pattern that may reduce gastric cancer risk, particularly when combined with other modifiable lifestyle factors.

Evidence

The polymorphism -251 A/T in the promoter region of the interleukin 8 gene and the risk of gastric cancer: case-control study

Authors: Felipe, Aledson Vitor

Published: April 28, 2010

In this case-control study comparing 104 non-cardia gastric cancer patients with 208 healthy controls, low vegetable intake was significantly more frequent in the cancer group (p=0.02). While vegetable intake did not retain independent significance in the final multivariate logistic regression model after adjusting for IL-8 genotype, fat consumption, and smoking, the univariate association suggests a protective dietary pattern worthy of consideration alongside other modifiable risk factors.

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Case-Control Study of Dietary Pattern and Other Risk Factors for Gastric Cancer

Authors: مهدوی, رضا, نعمتی, علی, نقی زاده باقی, عباس

Published: June 1, 1391

A case-control study comparing 42 gastric cancer patients with 86 healthy controls in Ardabil Province, Iran found that low intake of fresh vegetables was among the most significant dietary risk factors for gastric cancer (P<0.05). The study population of 128 adults (mean age 56.5 ± 12.8 years) was assessed using structured questionnaire interviews during 2010-2011. Statistical analysis via Chi-square and independent t-tests confirmed dietary pattern had a significant association with gastric cancer status.

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